Diflucan, commonly known by the brand name Fluconazole, is an antifungal medication used to treat various fungal infections, including vaginal candidiasis, yeast infections, and fungal infections of the blood, onychomycosis, trichomoniasis, systemic infections, gonorrhea, and in systemic symptoms following liver or vaginal surgery. It is also used for the treatment of systemic symptoms such as itching, burning, and discharge during sexual activity. Diflucan was the first oral antifungal approved by the FDA in the UK in 2003. It is a member of the fungal antibiotic family and is classified as a fluconazole. It is available in a range of dosage strengths, including 50mg and 100mg. Diflucan is important to improve the overall outcome of antifungal treatments and to prevent recurrence of antifungal infections following initial treatment.
The global use of antifungal drugs in medicine is expected to reach USD 3.5 billion by 2033,� with a projected compound annual growth rate (CAGR) ofixiridese of CAGR 6.8% from 5.5 to 10 million new cases, onychomycosis, systemic fungal infections, and vaginal candidiasis. With a market size of CAGR 1.2 billion in 2013, onychomycosis, systemic fungal infections, and vaginal candidiasis accounts for over 4% of onycoses, contributing significantly to the overall burden of fungal infections globally. With a market size of USD 1.07 billion in 2013, onychomycosis is expected to reach USD 1.08 billion by 2033, with a CAGR of Climb-to-Clinica ratio of 2 to 5.0. The Climb-to-Clinica ratio is thought to be higher for systemic symptoms due to onychomycosis, while for onycosis, the Climb-to-Systemic symptoms ratio is low.
The market for antifungals is highly competitive, with several major regions experiencing significant growth. Europe alone is the second-largest region with a market size of USD 1.2 billion in 2013 with a CAGR of Climb-to-Clinica ratio of 2.8% from 2 to 5.0. Asia Pacific, the Middle East, Latin America, and sub-continent areas are also experiencing significant growth due to their large populations, increasing awareness of fungal infections, and an expanding economy. North America is also seeing substantial growth due to its population, increasing healthcare expenditure, and an expanding economy. Australia is also seeing significant growth due to its population and increasing healthcare spending. The market for antifungals in this region is expected to grow significantly due to the increasing prevalence of onychomycosis and the expansion of healthcare infrastructure.
The antifungals market is segmented based on several criteria:
The market for antifungals is segmented into three main regions:
The market for antifungals is segmented by region:
The North American and Europe market for antifungals are expected to grow significantly due to the increasing prevalence of onychomycosis and the expanding economy. The Middle Market will see significant growth due to the high demand for antifungals due to its high efficacy and low cost. The LMP regions will have increasing healthcare spending and the increasing healthcare spending of the population. The LLP regions will have increasing healthcare facilities.
The cost of antifungals is influenced by the availability of generic drugs, the price of drugs, and pharmacy dispensing costs.
Fluconazole is used to treat serious fungal or yeast infections, including vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), other candida infections (including urinary tract infections, peritonitis [inflammation of the lining of the stomach], and infections that may occur in different parts of the body), or fungal (cryptococcal) meningitis. It is also used in children on life support called extracorporeal membrane oxygenation (ECMO). This medicine works by killing the fungus or yeast, or preventing its growth. Fluconazole is also used to prevent candidiasis in patients having bone marrow transplants who receive cancer or radiation treatment.
Direction to Use:
DIFLUCAN® ONE is administered orally. Use in AdultsFor vaginal candidiasis, fluconazole 150 mg (DIFLUCAN® ONE) should beadministered as a single oral dose. The median time to onset of symptom relief following a 150 mg single oral dose for thetreatment of vaginal candidiasis is one day. The range of time to onset of symptomrelief is one hour to nine days. Use in ChildrenSingle dose fluconazole is not recommended for use in children under 18 years of ageexcept under doctor supervision.
Side Effects
Common fluconazole side effects include nausea, headache, and stomach pain. Diarrhea is also possible. Mild side effects tend to resolve on their own or go away when you finish your treatment course. Serious fluconazole side effects such as skin rash, liver damage, and heart rhythm changes are also possible
ReferencesFluconazole tablets are available in oral dosage forms.
For treatment of vaginal candidiasis, fluconazole tablets should be administered as a single oral dose.Do not take fluconazole tablets within four weeks of receiving a prescription for:Gonorrhea, cystitis, or pain during urinationor any medication that contains lidocaine (e.g. codeine or morphine) or benzocaine (e.g. codeine, codeine, codeine, benzyl alcohol, codeine, isocarboxazide, phenethone, phenytoin, triethanolamine, methylmethanol, sorbitol, xanel, isopropyl alcohol, butyl glycol, and sorbitol tablets).Any of these may cause an allergic reaction. If these effects are not felt within one to four weeks of receiving fluconazole tablets, or if symptoms continue for more than a few days, consult your doctor.Do not start fluconazole tablets after three months of taking a single tablet of fluconazole for vaginal candidiasis.The half life of fluconazole in human skeletal muscle is 2.5 to 3 years. When used in patients who are at risk for skeletal muscle side effects (e.g. bone or joint problems), do not start fluconazole after two months of fluconazole for vaginal candidiasis.
Fluconazole should not be used in patients with asthma or with allergies to fluconazole or other anti-inflammatory medicines. Do not to take fluconazole if you have ever had an allergic reaction to any other quinapril-type medication of this group.
ichever columnPrecautions
Thrush is a fungal infection, commonly caused by a type of yeast called candida. Although candida is naturally present in the body, an imbalance can trigger thrush symptoms. Fluconazole 150mg (also known as Diflucan and other brand names) kills certain types of fungi and restores your body's natural balance.
Fluconazole treatment for thrush is simple - just one capsule to be swallowed with a glass of water. You can take this medicine at any time of day, with or without a meal.
Women taking fluconazole should see an improvement within a few days. Some women will notice improvement in 24 hours.
For men, the condition can take a little longer to clear up. The symptoms should clear up within a few days, although this can take up to a week.
If your condition hasn't cleared up within one week, you should consult a doctor.
Thrush is an infection which can occur without sexual contact, so it is not a sexually transmitted disease. However, the infection can be passed on during sex, so it is recommended that you should not have sex until the infection has cleared up.
If you regularly suffer from thrush, then it's advisable that both you and your partner have thrush treatment at the same time.
Taking too much can make you unwell, so contact your doctor or nearest hospital immediately if you take more than you should.
As with any medicine, there are side effects. Although a serious allergic reaction to fluconazole is rare. Common side effects (occurring in one in ten patients) include nausea, stomach discomfort, diarrhoea, wind, rash and headache. However, these side effects are usually mild and don't tend to last long. If symptoms persist, or are particularly severe, contact your doctor.
A full list of side effects is available in the manufacturer's.
You should not take fluconazole while you are pregnant, or if you are breastfeeding.
Do not take fluconazole if you've ever had an allergic reaction to any of its ingredients or any other medicines which you have taken to treat a fungal infection.
Tell your doctor before taking fluconazole if:
Tell your doctor about any other medicines you are taking, or have recently taken before taking fluconazole.
There is a very rare theoretical risk of abnormal heart rhythm if fluconazole is taken at the same time as some other medications -.
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine and must be read before taking the medicine. It is written for patients and gives information about taking or using a medicine.
See for help you book an appointment with the doctor.
Thrush is a fungal infection, commonly caused by a type of yeast called candida. Although candida is naturally present in the body, an imbalance can trigger thrush symptoms. Fluconazole 150mg (also known as Diflucan and other brand names) kills certain types of fungi and restores your body's natural balance.
Fluconazole treatment for thrush is simple - just one capsule to be swallowed with a glass of water. You can take this medicine at any time of day, with or without a meal.
Women taking fluconazole should see an improvement within a few days. Some women will notice improvement in 24 hours.
For men, the condition can take a little longer to clear up. The symptoms should clear up within a few days, although this can take up to a week.
If your condition hasn't cleared up within one week, you should consult a doctor.
Thrush is an infection which can occur without sexual contact, so it is not a sexually transmitted disease. However, the infection can be passed on during sex, so it is recommended that you should not have sex until the infection has cleared up.
If you regularly suffer from thrush, then it's advisable that both you and your partner have thrush treatment at the same time.
Taking too much can make you unwell, so contact your doctor or nearest hospital immediately if you take more than you should.
As with any medicine, there are side effects. Although a serious allergic reaction to fluconazole is rare. Common side effects (occurring in one in ten patients) include nausea, stomach discomfort, diarrhoea, wind, rash and headache. However, these side effects are usually mild and don't tend to last long. If symptoms persist, or are particularly severe, contact your doctor.
A full list of side effects is available in the manufacturer's.
You should not take fluconazole while you are pregnant, or if you are breastfeeding.
Do not take fluconazole if you've ever had an allergic reaction to any of its ingredients or any other medicines which you have taken to treat a fungal infection.
Tell your doctor before taking fluconazole if:
Tell your doctor about any other medicines you are taking, or have recently taken before taking fluconazole.
There is a very rare theoretical risk of abnormal heart rhythm if fluconazole is taken at the same time as some other medications -.
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine and must be read before taking the medicine. It is written for patients and gives information about taking or using a medicine.
See also.
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and give information about taking or using a medicine.
It is a medicine for patients and are similar to a medication.
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